Adrian used himself as a subject and demonstrated the phenomenon of alpha blocking, where opening his eyes suppressed alpha rhythms.
3.
The S (-) enantiomer accounts for the beta blocking activity whereas the S (-) and R ( + ) enantiomer have alpha blocking activity.
4.
Mulholland and Peper ( 1971 ) showed that occipital alpha increases with eyes open and not focused, and is disrupted by visual focusing; a rediscovery of alpha blocking.
5.
Beck published studies of spontaneous electrical potentials detected from the brains of dogs and rabbits, and was the first to document alpha blocking, where light alters rhythmic oscillations, in 1890.
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